Dr Pascale du Pré is a Paediatric Intensive Care Consultant at Great Ormond Street Hospital, since 2018. In the department, she has been actively involved in research and presentations through Webinars, especially during the COVID-19 pandemic. She has also had a number of publications and has contributed to the formation of guidelines in the management of the COVID-19 disease. In her role as the Medical Lead for Child Death Reviews, she critically reviews all deaths within the Trust and is responsible for preparing and submitting quarterly Learning from Death reports and presenting these at Governance Meetings.
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News & Publications
Alders N, Penner J, Grant K, Patterson C, Hassell J, MacDermott N, Pincott S, Bamford A, du Pré P, Johnson M, Moshal K, COVID-19 Pandemic Preparedness in a United Kingdom Tertiary and Quaternary Children’s Hospital: Tales of the Unexpected, Journal of the Pediatric Infectious Diseases Society, 2020 Oct doi:10.1093/jpids/piaa135
Deep A, Upadhyay G, du Pré P, Lillie J et al Acute kidney injury in Pediatric Inflammatory Multi-system Syndrome Temporally associated with SARS-CoV-2 pandemic (PIMS-TS): experience from Pediatric Intensive Care Units across United Kingdom. CCM 2020
Stewart DJ, Hartley JC, Johnson M, Marks SD, du Pré P, Stojanovic J. Renal dysfunction in hospitalised children with COVID-19. Lancet Child Adolesc Health. 2020 Jun 15:S2352-4642(20)30178-4. doi: 10.1016/S2352-4642(20)30178-4. Online ahead of print. PMID: 32553126 Free PMC article.
Issitt RW, Booth J, Bryant WA, Spiridou A, Taylor AM, du Pré P., Ramnarayan P, Hartley J, Cortina-Borja M, Moshal K, Dunn H, Hemingway H, Sebire NJ. Children with COVID-19 at a specialist centre: initial experience and outcome. Lancet Child Adolesc Health. 2020 Jun 22:S2352-4642(20)30204-2. doi: 10.1016/S2352-4642(20)30204-2. Online ahead of print. PMID: 32585186 Free PMC article.
Orf K, Rogosic S, Dexter D, Ancliff P, Badle S, Brierley J, Cheng D, Dalton C, Dixon G, du Pré P., Grandjean L, Ghorashian S, Mittal P, O'Connor D, Pavasovic V, Rao A, Samarasinghe S, Vora A, Bamford A, Bartram J. Remdesivir during induction chemotherapy for newly diagnosed paediatric acute lymphoblastic leukaemia with concomitant SARS-CoV-2 infection. Br J Haematol. 2020 Jul 11. doi: 10.1111/bjh.17014. Online ahead of print. PMID: 32652563
Davies P, Evans C, Kanthimathinathan HK, Lillie J, Brierley J, Waters G, Johnson M, Griffiths B, du Pré P., Mohammad Z, Deep A, Playfor S, Singh D, Inwald D, Jardine M, Ross O, Shetty N, Worrall M, Sinha R, Koul A, Whittaker E, Vyas H, Scholefield BR, Ramnarayan P. Intensive care admissions of children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) in the UK: a multicentre observational study. Lancet Child Adolesc Health. 2020 Jul 9:S2352-4642(20)30215-7. doi: 10.1016/S2352-4642(20)30215-7. Online ahead of print. PMID: 32653054
Lanyon N, du Pré P., Thiruchelvam T, Ray S, Johnson M, Peters MJ. Critical paediatric COVID-19: varied presentations but good outcomes. Arch Dis Child. 2020 Jun 29:archdischild-2020-319602. doi: 10.1136/archdischild-2020-319602. Online ahead of print. PMID: 32601086
Walsh A, Booth R, Rajani K, Cochrane L, Peters M, du Pré P. Introduction of a prescribing ward round to reduce prescribing errors on a paediatric intensive care unit. Arch Dis Child Educ Pract Ed. 2020 Jul 3:edpract-2019-318732. doi: 10.1136/archdischild-2019-318732. Online ahead of print. PMID: 32620582
du Pré P, Tissières P, Brierley J. Book Chapter 53 Discontinuation of Life-Sustaining Therapy in Intensive Care: Ethical and Legal Issues. In: Munoz R et al editors. Critical Care of Children with Heart Disease. Basic Medical and Surgical Concepts. Springer Nature 2019.
Sidgwick P, du Pre P, Kerr-Ellit T, Downie J, Skellett S 017 Talking to families when death becomes a likely outcome – a pilot simulation programme to improve end of life conversations during and around PICU admission. December 2018 Archives of Disease in Childhood 103(Suppl 2):A7.3-A8
du Pre P, Brierley J, Challenges in managing parental expectations in paediatric care. Birtish Journal of Haematology. September 2018
Sidgwick P, du Pre P, Skellett S. Abstract PD-037: Talking to Families when death becomes a likely outcome – a pilot simulation programme to improve end of life conversations during and around PICU admission. [Abstract] June 2018. Pediatric Critical Care Medicine 19:41
du Pre P, Brierley J, Koffman J. G480(P) The experiences, attitudes and practices of nurses working in a paediatric intensive care unit caring for babies and children at the end of life: a qualitative study. March 2018 Archives of Disease in Childhood 103(Suppl 1):A196.2-A196. Conference: Royal College of Paediatrics and Child Health, Abstracts of the Annual Conference, 13–15 March 2018, SEC, Glasgow, Children First – Ethics, Morality and Advocacy in Childhood, The Journal of the Royal College of Paediatrics and Child Health
Green CJ, du Pré P, Elahi N, Dunkley P, McIntyreGreen CJ, du Pre P, Elahi N, Dunkley P, McIntyre AS. Omission after admission: failure in prescribed medications being given to inpatients. Clinical Medicine 2009, Vol 9, No 6: 515-8
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